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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOCS7
All Species:
11.21
Human Site:
S254
Identified Species:
20.56
UniProt:
O14512
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14512
NP_055413.1
581
62969
S254
S
L
T
D
M
G
G
S
A
G
R
E
L
D
A
Chimpanzee
Pan troglodytes
XP_512211
535
59559
H197
S
L
K
S
S
A
S
H
N
G
D
L
R
L
H
Rhesus Macaque
Macaca mulatta
XP_001082440
360
39867
K64
E
L
G
Y
S
K
K
K
M
L
G
G
F
G
F
Dog
Lupus familis
XP_548159
411
45633
T114
V
S
F
S
P
L
F
T
G
E
T
V
S
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHQ2
579
62765
S252
S
L
T
D
M
G
G
S
A
V
R
E
L
D
T
Rat
Rattus norvegicus
XP_001081372
564
60962
S237
S
L
T
D
M
G
G
S
A
V
R
E
L
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506079
518
56852
F191
G
P
E
P
S
G
G
F
P
R
P
A
A
S
P
Chicken
Gallus gallus
XP_423895
264
29931
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684929
733
79803
C406
K
L
F
R
T
K
S
C
S
G
S
N
N
L
L
Tiger Blowfish
Takifugu rubipres
NP_001116335
565
61771
T237
S
L
V
D
M
A
T
T
A
G
P
E
Q
D
T
Fruit Fly
Dros. melanogaster
NP_523390
1016
110741
N660
N
L
D
N
D
K
L
N
N
N
N
N
N
N
N
Honey Bee
Apis mellifera
XP_397211
804
90105
A427
S
H
T
P
V
H
L
A
M
P
K
G
I
S
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792866
847
94386
A245
T
V
P
L
Q
R
K
A
S
V
R
N
D
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.6
43
69.5
N.A.
97.4
95.1
N.A.
24.1
42.6
N.A.
38.2
52.3
22
24.8
N.A.
27.8
Protein Similarity:
100
36.8
49.5
69.7
N.A.
98.1
95.8
N.A.
34.4
43.7
N.A.
48.2
62.4
32.1
39.2
N.A.
39
P-Site Identity:
100
20
6.6
0
N.A.
86.6
93.3
N.A.
13.3
0
N.A.
13.3
53.3
6.6
13.3
N.A.
6.6
P-Site Similarity:
100
20
6.6
6.6
N.A.
86.6
93.3
N.A.
13.3
0
N.A.
20
60
33.3
40
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
16
0
16
31
0
0
8
8
0
16
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
31
8
0
0
0
0
0
8
0
8
31
0
% D
% Glu:
8
0
8
0
0
0
0
0
0
8
0
31
0
0
0
% E
% Phe:
0
0
16
0
0
0
8
8
0
0
0
0
8
0
8
% F
% Gly:
8
0
8
0
0
31
31
0
8
31
8
16
0
8
0
% G
% His:
0
8
0
0
0
8
0
8
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% I
% Lys:
8
0
8
0
0
24
16
8
0
0
8
0
0
0
0
% K
% Leu:
0
62
0
8
0
8
16
0
0
8
0
8
24
24
8
% L
% Met:
0
0
0
0
31
0
0
0
16
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
0
8
16
8
8
24
16
8
8
% N
% Pro:
0
8
8
16
8
0
0
0
8
8
16
0
0
0
8
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
8
0
8
0
0
0
8
31
0
8
0
0
% R
% Ser:
47
8
0
16
24
0
16
24
16
0
8
0
8
16
8
% S
% Thr:
8
0
31
0
8
0
8
16
0
0
8
0
0
0
16
% T
% Val:
8
8
8
0
8
0
0
0
0
24
0
8
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _